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Rabbit Polyclonal Antibody to TCEB1

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别名:Transcription elongation factor B polypeptide 1, Elongin 15 kDa subunit, Elongin-C, EloC, RNA polymerase II transcription factor SIII subunit C, SIII p15, TCEB1
应用:WB,IHC
反应种属:Human
规格:50μl/100μl

Description
This gene encodes the protein elongin C, which is a
subunit of the transcription factor B (SIII) complex. The SIII
complex is composed of elongins A/A2, B and C. It activates
elongation by RNA polymerase II by suppressing transient pausing of
the polymerase at many sites within transcription units. Elongin A
functions as the transcriptionally active component of the SIII
complex, whereas elongins B and C are regulatory subunits. Elongin
A2 is specifically expressed in the testis, and capable of forming
a stable complex with elongins B and C. The von Hippel-Lindau tumor
suppressor protein binds to elongins B and C, and thereby inhibits
transcription elongation.
Specification
Aliases Transcription elongation factor B polypeptide 1, Elongin 15 kDa subunit, Elongin-C, EloC, RNA polymerase II transcription factor SIII subunit C, SIII p15, TCEB1
Entrez GeneID 6921
Swissprot Q15369
WB Predicted band size 12.5kDa
Host/Isotype Rabbit IgG
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen This TCEB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 69-98 amino acids from the C-terminal region of human TCEB1.
Formulation Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Application
WB 1/1000
IHC 1/100-1/500

All lanes : Anti-TCEB1 Antibody (C-term) at 1:1000 dilution
Lane 1: Hela whole cell lysate
Lane 2: PC-3 whole cell lysate

Lysates/proteins at 20 µg per lane.

Secondary
Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.

Predicted band size : 12 kDa

Blocking/Dilution buffer: 5% NFDM/TBST.

TCEB1 Antibody (C-term) (P33465)immunohistochemistry analysis in formalin fixed and paraffin embedded human prostate carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of TCEB1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。