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瑞威尔生物科技 REVERE

Rabbit Polyclonal Antibody to TCEB2

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别名:Transcription elongation factor B polypeptide 2, Elongin 18 kDa subunit, Elongin-B, EloB, RNA polymerase II transcription factor SIII subunit B, SIII p18, TCEB2
应用:WB
反应种属:Human
规格:50μl/100μl

Description
This gene encodes the protein elongin B, which is a
subunit of the transcription factor B (SIII) complex. The SIII
complex is composed of elongins A/A2, B and C. It activates
elongation by RNA polymerase II by suppressing transient pausing of
the polymerase at many sites within transcription units. Elongin A
functions as the transcriptionally active component of the SIII
complex, whereas elongins B and C are regulatory subunits. Elongin
A2 is specifically expressed in the testis, and capable of forming
a stable complex with elongins B and C. The von Hippel-Lindau tumor
suppressor protein binds to elongins B and C, and thereby inhibits
transcription elongation. Two alternatively spliced transcript
variants encoding different isoforms have been described for this
gene. Pseudogenes have been identified on chromosomes 11 and 13.
Specification
Aliases Transcription elongation factor B polypeptide 2, Elongin 18 kDa subunit, Elongin-B, EloB, RNA polymerase II transcription factor SIII subunit B, SIII p18, TCEB2
Entrez GeneID 6923
Swissprot Q15370
WB Predicted band size 13.1kDa
Host/Isotype Rabbit IgG
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen This TCEB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 21-48 amino acids from the Central region of human TCEB2.
Formulation Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Application
WB 1/1000

TCEB2 Antibody (Center) (Cat. #P31446) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the TCEB2 antibody detected the TCEB2 protein (arrow).

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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。