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瑞威尔生物科技 REVERE

Rabbit Polyclonal Antibody to TCF7L1

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别名:Transcription factor 7-like 1; HMG box transcription factor 3; TCF-3; TCF7L1; TCF3
应用:WB
反应种属:Human,Mouse
规格:50μl/100μl

Description
Participates in the Wnt signaling pathway. Binds to DNA and acts as a repressor in the absence of CTNNB1, and as an activator in its presence. Necessary for the terminal differentiation of epidermal cells, the formation of keratohyalin granules and the development of the barrier function of the epidermis By similarity. Down-regulates NQO1, leading to increased mitomycin c resistance.Sagara N., Cancer Res. 60:5959-5962(2000).Hillier L.W., Nature 434:724-731(2005).Castrop J., Nucleic Acids Res. 20:611-611(1992).
Specification
Aliases Transcription factor 7-like 1; HMG box transcription factor 3; TCF-3; TCF7L1; TCF3
Entrez GeneID 83439;
Swissprot Q9HCS4
WB Predicted band size 63kDa
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse
Immunogen Synthesized peptide derived from internal of human TCF7L1.
Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Application
WB 1/500-1/3000

Western blot analysis of extracts from 3T3 cells, using TCF7L1 antibody P42640.

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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。