别名:Thyrotroph embryonic factor, TEF, KIAA1655应用:WB
反应种属:Human, Mouse, Rat
规格:50μl/100μl
Description |
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Thyrotroph embryonic factor (TEF), a transcription factor, is a member of the PAR (proline and acidic amino acid-rich) subfamily of basic region/leucine zipper (bZIP) transcription factors. It is expressed in a broad range of cells and tissues in adult animals, however, during embryonic development, TEF expression appears to be restricted to the developing anterior pituitary gland, coincident with the appearance of thyroid-stimulating hormone, beta (TSHB). Indeed, TEF can bind to, and transactivate the TSHB promoter. It shows homology (in the functional domains) with other members of the PAR-bZIP subfamily of transcription factors, which include albumin D box-binding protein (DBP), human hepatic leukemia factor (HLF) and chicken vitellogenin gene-binding protein (VBP); VBP is considered the chicken homologue of TEF. Different members of the subfamily can readily form heterodimers, and share DNA-binding, and transcriptional regulatory properties. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]. |
Specification | |
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Aliases | Thyrotroph embryonic factor, TEF, KIAA1655 |
Entrez GeneID | 7008 |
Swissprot | Q10587 |
WB Predicted band size | 33.2kDa |
Host/Isotype | Rabbit IgG |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human, Mouse, Rat |
Immunogen | This TEF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 213-240 amino acids from the C-terminal region of human TEF. |
Formulation | Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Application | |
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WB | 1/1000-1/2000 |
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Anti-TEF Antibody (C-term) at 1:2000 dilution + human cerebellum lysate
Lysates/proteins at 20 µg per lane. Secondary Predicted band size : 33 kDa Blocking/Dilution buffer: 5% NFDM/TBST. |
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TEF Antibody (C-term) (Cat. #P34012) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the TEF antibody detected the TEF protein (arrow). |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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