别名:Dual specificity testis-specific protein kinase 2, Testicular protein kinase 2, TESK2应用:WB,IHC
反应种属:Human
规格:50μl/100μl
Description |
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TESK2 is a dual specificity protein kinase activity catalyzing autophosphorylation and phosphorylation of exogenous substrates on both serine/threonine and tyrosine residues. TESK2 phosphorylates cofilin at Ser-3. It may play an important role in spermatogenesis. This nuclear enzyme is thought to be activated by autophosphorylation on Ser-219. Expression is predominantly in testis and prostate, with highest concentrations in nongerminal Sertoli cells. |
Specification | |
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Aliases | Dual specificity testis-specific protein kinase 2, Testicular protein kinase 2, TESK2 |
Entrez GeneID | 10420 |
Swissprot | Q96S53 |
WB Predicted band size | 63.6kDa |
Host/Isotype | Rabbit IgG |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | This TESK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 210-240 amino acids from the Central region of human TESK2. |
Formulation | Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
Application | |
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WB | 1/500 |
IHC | 1/100-1/500 |
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Anti-TESK2 Antibody (Center) at 1:500 dilution + HL-60 whole cell lysate
Lysates/proteins at 20 µg per lane. Secondary Predicted band size : 64 kDa Blocking/Dilution buffer: 5% NFDM/TBST. |
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Formalin-fixed and paraffin-embedded human testis tissue reacted with TESK2 antibody (Center)(Cat.#AP7812f), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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