别名:F3; Tissue factor; TF; Coagulation factor III; Thromboplastin; CD antigen CD142应用:WB,IHC
反应种属:Human
规格:50μl/100μl
Description |
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coagulation factor III, tissue factor(F3) Homo sapiens This gene encodes coagulation factor III which is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces. There are 3 distinct domains of this factor: extracellular, transmembrane, and cytoplasmic. This protein is the only one in the coagulation pathway for which a congenital deficiency has not been described. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010], |
Specification | |
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Aliases | F3; Tissue factor; TF; Coagulation factor III; Thromboplastin; CD antigen CD142 |
Entrez GeneID | 2152 |
Swissprot | P13726 |
WB Predicted band size | 40kDa |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | The antiserum was produced against synthesized peptide derived from human Coagulation Factor III around the phosphorylation site of Ser290. AA range:246-295 |
Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Application | |
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WB | 1/500 – 1/2000 |
IHC | 1/100 – 1/300 |
ELISA | 1/20000 |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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