库存-现货
瑞威尔生物科技 REVERE

Rabbit Polyclonal Antibody to TF (phospho Ser290)

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别名:F3; Tissue factor; TF; Coagulation factor III; Thromboplastin; CD antigen CD142
应用:WB,IHC
反应种属:Human
规格:50μl/100μl

Description
coagulation factor III, tissue factor(F3) Homo sapiens This gene encodes coagulation factor III which is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces. There are 3 distinct domains of this factor: extracellular, transmembrane, and cytoplasmic. This protein is the only one in the coagulation pathway for which a congenital deficiency has not been described. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010],
Specification
Aliases F3; Tissue factor; TF; Coagulation factor III; Thromboplastin; CD antigen CD142
Entrez GeneID 2152
Swissprot P13726
WB Predicted band size 40kDa
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen The antiserum was produced against synthesized peptide derived from human Coagulation Factor III around the phosphorylation site of Ser290. AA range:246-295
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Application
WB 1/500 – 1/2000
IHC 1/100 – 1/300
ELISA 1/20000


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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。