Rabbit Polyclonal Antibody to TFIP8

包装: 1G|100G|500G|1KG|100KG

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别名:Tumor necrosis factor; alpha-induced protein 8; Head and neck tumor and metastasis-related protein; TNF-induced protein GG2-1; SCC-S2
应用:WB,IHC,ICC
反应种属:Human,Mouse
规格：50μl/100μl

Description
Acts as a negative mediator of apoptosis and may play a role in tumor progression. Suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation.Horrevoets A.J.G., Blood 93:3418-3431(1999).Kumar D., J. Biol. Chem. 275:2973-2978(2000).You Z., J. Biol. Chem. 276:26398-26404(2001).

Description

Acts as a negative mediator of apoptosis and may play a role in tumor progression. Suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation.Horrevoets A.J.G., Blood 93:3418-3431(1999).Kumar D., J. Biol. Chem. 275:2973-2978(2000).You Z., J. Biol. Chem. 276:26398-26404(2001).

Specification
Aliases	Tumor necrosis factor; alpha-induced protein 8; Head and neck tumor and metastasis-related protein; TNF-induced protein GG2-1; SCC-S2
Entrez GeneID	25816;
Swissprot	O95379
WB Predicted band size	23kDa
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse
Immunogen	Synthesized peptide derived from internal of human TFIP8.
Formulation	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Application
WB	1/500-1/3000
IHC	1/50-1/100
ICC	1/100-1/500

	Western blot analysis of extracts from HUVEC cells, using TFIP8 antibody P41890.
	Immunofluorescence analysis of A549 cells, using TFIP8 antibody P41890.
	Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue using TFIP8 antibody P41890.