Rabbit Polyclonal Antibody to TGM4

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别名:TGP; hTGP
应用:WB,IHC
反应种属:Human
规格：50μl/100μl

Description
Transglutaminase 4 also known as TGM4, TGP or hTGP, is a typical TGase that is specifically expressed in prostate tissue. TGM4 are intercellularly localizing, Ca2+-dependent enzymes, which catalyze the formation of isopeptide bonds by transferring an amine on to glutaminyl residues, thereby cross-linking glutamine residues and lysine residues in substrate proteins. TGases influence numerous biological processes including blood coagulation, epidermal differentiation, seminal fluid coagulation, fertilization, cell differentiation and apoptosis.

Description

Transglutaminase 4 also known as TGM4, TGP or hTGP, is a typical TGase that is specifically expressed in prostate tissue. TGM4 are intercellularly localizing, Ca2+-dependent enzymes, which catalyze the formation of isopeptide bonds by transferring an amine on to glutaminyl residues, thereby cross-linking glutamine residues and lysine residues in substrate proteins. TGases influence numerous biological processes including blood coagulation, epidermal differentiation, seminal fluid coagulation, fertilization, cell differentiation and apoptosis.

Specification
Aliases	TGP; hTGP
Swissprot	P49221
WB Predicted band size	77 kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Fusion protein of human TGM4
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Application
WB	1/500-1/2000
IHC	1/25-1/100
ELISA	1/2000-1/5000

	Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane 1-5: Hela, lncap, skov3, 293T and TM4 cell, Primary antibody: P08899(TGM4 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds
	The image is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using P08899(TGM4 Antibody) at dilution 1/20. (Original magnification: ×200)
	The image is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using P08899(TGM4 Antibody) at dilution 1/20. (Original magnification: ×200)