别名:CYP5; CYP5A1; Cytochrome P450 5A1; cytochrome P450; family 5应用:WB
反应种属:Human
规格:50μl/100μl
Description |
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This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to thromboxane A2, a potent vasoconstrictor and inducer of platelet aggregation. The enzyme plays a role in several pathophysiological processes including hemostasis, cardiovascular disease, and stroke. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.Yokoyama C., Biochem. Biophys. Res. Commun. 178:1479-1484(1991).Ohashi K., J. Biol. Chem. 267:789-793(1992).Miyata A., Eur. J. Biochem. 224:273-279(1994). |
Specification | |
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Aliases | CYP5; CYP5A1; Cytochrome P450 5A1; cytochrome P450; family 5 |
Entrez GeneID | 6916; |
Swissprot | P24557 |
WB Predicted band size | 61kDa |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Synthesized peptide derived from C-terminal of human THAS. |
Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Application | |
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WB | 1/500-1/3000 |
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Western blot analysis of extracts from Jurkat cells, using THAS antibody P42723. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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