别名:HTATIP; TI60; Tat-interactive protein-60;应用:IHC
反应种属:Human,Mouse,Rat
规格:50μl/100μl
Description |
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The protein encoded by this gene belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. This protein is a histone acetylase that has a role in DNA repair and apoptosis and is thought to play an important role in signal transduction. Alternative splicing of this gene results in multiple transcript variants.Kamine J., Virology 216:357-366(1996)Sheridan A.M., Mol. Cell. Biol. 21:4470-4481(2001)Legube G., Gene 310:161-168(2003) |
Specification | |
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Aliases | HTATIP; TI60; Tat-interactive protein-60; |
Entrez GeneID | 10524; |
Swissprot | Q92993 |
WB Predicted band size | 58kDa |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human,Mouse,Rat |
Immunogen | Peptide sequence around phosphorylation site of Serine 90(P-G-S(p)-P-E) derived from Human Tip60. |
Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Application | |
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IHC | 1/50-1/100 |
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Immunohistochemical analysis of paraffin-embedded human brain tissue using Tip60 (Phospho-Ser90) antibody P40514 (left)or the same antibody preincubated with blocking peptide (right). |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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