中文 
别名:TOLL; CD284; TLR-4; ARMD10应用:WB,IHC
反应种属:Human
规格：50μl/100μl
| Description |
|---|
| The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene. |
| Specification | |
|---|---|
| Aliases | TOLL; CD284; TLR-4; ARMD10 |
| Entrez GeneID | 7099; |
| Swissprot | O00206 |
| WB Predicted band size | 96kDa |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Fusion protein corresponding to a region derived from internal residues of human toll-like receptor 4 |
| Formulation | Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol. |
| Application | |
|---|---|
| WB | 1/500-1/2000 |
| IHC | 1/25-1/100 |
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Gel: 6%SDS-PAGE Lysate: 60ug K562 cell Primary antibody: 1/550 dilution Secondary antibody dilution: 1/8000 Exposure time: 1 minute |
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Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue using P42749 at dilution 1/25. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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