Rabbit Polyclonal Antibody to TMPRSS13

包装: 1G|100G|500G|1KG|100KG

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别名:Transmembrane protease serine 13, 3421-, Membrane-type mosaic serine protease, Mosaic serine protease, TMPRSS13, MSP, TMPRSS11
应用:WB,IHC
反应种属:Human
规格：50μl/100μl

Description
TMPRSS13 is a cell membrane serine protease. It is a member of a larger family of membrane attached serine proteases, a poorly defined group that includes TMPRSS11A, B, C, D, E, F, Hepsin, Corin, Matriptase 1, 2 and 3. TMPRSS13 has a domain structure of an aminoterminal cytoplasmic domain, which is much longer than the other TMPRSS family members, followed by a transmembrane domain, an SRCR domain (Scavenger receptor cysteine rich), an LDL receptor like domain, another SRCR domain, followed by the trypsin like serine protease domain. The cytoplasmic domain contains a number of tandem repeat elements, the function of which is not clear, but which may play a regulatory role.

Description

TMPRSS13 is a cell membrane serine protease. It is a member of a larger family of membrane attached serine proteases, a poorly defined group that includes TMPRSS11A, B, C, D, E, F, Hepsin, Corin, Matriptase 1, 2 and 3. TMPRSS13 has a domain structure of an aminoterminal cytoplasmic domain, which is much longer than the other TMPRSS family members, followed by a transmembrane domain, an SRCR domain (Scavenger receptor cysteine rich), an LDL receptor like domain, another SRCR domain, followed by the trypsin like serine protease domain. The cytoplasmic domain contains a number of tandem repeat elements, the function of which is not clear, but which may play a regulatory role.

Specification
Aliases	Transmembrane protease serine 13, 3421-, Membrane-type mosaic serine protease, Mosaic serine protease, TMPRSS13, MSP, TMPRSS11
Entrez GeneID	84000
Swissprot	Q9BYE2
WB Predicted band size	63.2kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	This TMPRSS13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 431-460 amino acids from the C-terminal region of human TMPRSS13.
Formulation	Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Application
WB	1/1000
IHC	1/100-1/500

	TMPRSS13 Antibody (C-term) (Cat. #P31510) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the TMPRSS13 antibody detected the TMPRSS13 protein (arrow).
	TMPRSS13 Antibody (C-term) (P31510)immunohistochemistry analysis in formalin fixed and paraffin embedded human prostate tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of TMPRSS13 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.