Rabbit Polyclonal Antibody to TNF12

包装: 1G|100G|500G|1KG|100KG

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别名:Tumor necrosis factor ligand superfamily member 12; TNF-related weak inducer of apoptosis; TWEAK; APO3 ligand; Tumor necrosis factor ligand superfamily member 12
应用:WB,IHC,ICC
反应种属:Human,Mouse
规格：50μl/100μl

Description
Binds to FN14 and possibly also to TNRFSF12/APO3. Weak inducer of apoptosis in some cell types. Mediates NF-kappa-B activation. Promotes angiogenesis and the proliferation of endothelial cells. Also involved in induction of inflammatory cytokines. Promotes IL8 secretion.Chicheportiche Y., J. Biol. Chem. 272:32401-32410(1997).Marsters S.A., Curr. Biol. 8:525-528(1998).Clark H.F., Genome Res. 13:2265-2270(2003).

Description

Binds to FN14 and possibly also to TNRFSF12/APO3. Weak inducer of apoptosis in some cell types. Mediates NF-kappa-B activation. Promotes angiogenesis and the proliferation of endothelial cells. Also involved in induction of inflammatory cytokines. Promotes IL8 secretion.Chicheportiche Y., J. Biol. Chem. 272:32401-32410(1997).Marsters S.A., Curr. Biol. 8:525-528(1998).Clark H.F., Genome Res. 13:2265-2270(2003).

Specification
Aliases	Tumor necrosis factor ligand superfamily member 12; TNF-related weak inducer of apoptosis; TWEAK; APO3 ligand; Tumor necrosis factor ligand superfamily member 12
Entrez GeneID	407977;8742;
Swissprot	O43508
WB Predicted band size	27kDa
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse
Immunogen	Synthesized peptide derived from internal of human TNF12.
Formulation	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Application
WB	1/500-1/3000
IHC	1/50-1/100
ICC	1/100-1/500

	Western blot analysis of extracts from COLO cells, HUVEC cells and 293 cells, using TNF12 antibody P41867.
	Immunofluorescence analysis of HeLa cells, using TNF12 antibody P41867.
	Immunohistochemistry analysis of paraffin-embedded human brain tissue using TNF12 antibody P41867.