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瑞威尔生物科技 REVERE

Rabbit Polyclonal Antibody to TNFRSF25

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别名:Tumor necrosis factor receptor superfamily member 25, Apo-3, Apoptosis-inducing receptor AIR, Apoptosis-mediating receptor DR3, Apoptosis-mediating receptor TRAMP, Death receptor 3, Lymphocyte-associated receptor of death, LARD, Protein WSL, Protein WSL-1, TNFRSF25, APO3, DDR3, DR3, TNFRSF12, WSL, WSL1
应用:WB
反应种属:Human
规格:50μl/100μl

Description
The protein encoded by this gene is a member of the
TNF-receptor superfamily. This receptor is expressed preferentially
in the tissues enriched in lymphocytes, and it may play a role in
regulating lymphocyte homeostasis. This receptor has been shown to
stimulate NF-kappa B activity and regulate cell apoptosis. The
signal transduction of this receptor is mediated by various death
domain containing adaptor proteins. Knockout studies in mice
suggested the role of this gene in the removal of self-reactive T
cells in the thymus. Multiple alternatively spliced transcript
variants of this gene encoding distinct isoforms have been
reported, most of which are potentially secreted molecules. The
alternative splicing of this gene in B and T cells encounters a
programmed change upon T-cell activation, which predominantly
produces full-length, membrane bound isoforms, and is thought to be
involved in controlling lymphocyte proliferation induced by T-cell
activation.
Specification
Aliases Tumor necrosis factor receptor superfamily member 25, Apo-3, Apoptosis-inducing receptor AIR, Apoptosis-mediating receptor DR3, Apoptosis-mediating receptor TRAMP, Death receptor 3, Lymphocyte-associated receptor of death, LARD, Protein WSL, Protein WSL-1, TNFRSF25, APO3, DDR3, DR3, TNFRSF12, WSL, WSL1
Entrez GeneID 8718
Swissprot Q93038
WB Predicted band size 45.4kDa
Host/Isotype Rabbit IgG
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen This TNFRSF25 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 214-242 amino acids from the Central region of human TNFRSF25.
Formulation Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Application
WB 1/1000

TNFRSF25 Antibody (Center) (Cat. #P31787) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the TNFRSF25 antibody detected the TNFRSF25 protein (arrow).

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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。