Rabbit Polyclonal Antibody to TNFRSF6B (N-term)

包装: 1G|100G|500G|1KG|100KG

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别名:Tumor necrosis factor receptor superfamily member 6B, Decoy receptor 3, DcR3, Decoy receptor for Fas ligand, M68, TNFRSF6B, DCR3, TR6
应用:WB
反应种属:Human
规格：50μl/100μl

Description
This gene belongs to the tumor necrosis factor receptor superfamily. The encoded protein is postulated to play a regulatory role in suppressing FasL- and LIGHT-mediated cell death. It acts as a decoy receptor that competes with death receptors for ligand binding. Overexpression of this gene has been noted in gastrointestinal tract tumors, and it is located in a gene-rich cluster on chromosome 20, with other potentially tumor-related genes. Two transcript variants encoding the same isoform, but differing in the 5′ UTR, have been observed for this gene.

Description

This gene belongs to the tumor necrosis factor receptor
superfamily. The encoded protein is postulated to play a regulatory
role in suppressing FasL- and LIGHT-mediated cell death. It acts as
a decoy receptor that competes with death receptors for ligand
binding. Overexpression of this gene has been noted in
gastrointestinal tract tumors, and it is located in a gene-rich
cluster on chromosome 20, with other potentially tumor-related
genes. Two transcript variants encoding the same isoform, but
differing in the 5′ UTR, have been observed for this gene.

Specification
Aliases	Tumor necrosis factor receptor superfamily member 6B, Decoy receptor 3, DcR3, Decoy receptor for Fas ligand, M68, TNFRSF6B, DCR3, TR6
Entrez GeneID	8771
Swissprot	O95407
WB Predicted band size	32.7kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	This TNFRSF6B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 22-48 amino acids from the N-terminal region of human TNFRSF6B.
Formulation	Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Application
WB	1/2000

All lanes : Anti-TNFRSF6B Antibody (N-term) at 1:2000 dilution
Lane 1: HUVEC whole cell lysate
Lane 2: Hela whole cell lysate
Lane 3: PC-3 whole cell lysate
Lane 4: HCT116 whole cell lysate
Lane 5: SW480 whole cell lysate

Lysates/proteins at 20 µg per lane.

Secondary
Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.

Predicted band size : 33 kDa

Blocking/Dilution buffer: 5% NFDM/TBST.