别名:Trinucleotide repeat-containing gene 6A protein, CAG repeat protein 26, EMSY interactor protein, GW182 autoantigen, Protein GW1, Glycine-tryptophan protein of 182 kDa, TNRC6A, CAGH26, KIAA1460, TNRC6应用:WB
反应种属:Human, Mouse
规格:50μl/100μl
Description |
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Plays a role in RNA-mediated gene silencing by both micro-RNAs (miRNAs) and short interfering RNAs (siRNAs). Required for miRNA-dependent repression of translation and for siRNA- dependent endonucleolytic cleavage of complementary mRNAs by argonaute family proteins. As scaffoldng protein associates with argonaute proteins bound to partially complementary mRNAs and simultaneously can recruit CCR4-NOT and PAN deadenylase complexes. |
Specification | |
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Aliases | Trinucleotide repeat-containing gene 6A protein, CAG repeat protein 26, EMSY interactor protein, GW182 autoantigen, Protein GW1, Glycine-tryptophan protein of 182 kDa, TNRC6A, CAGH26, KIAA1460, TNRC6 |
Entrez GeneID | 27327 |
Swissprot | Q8NDV7 |
WB Predicted band size | 210.3kDa |
Host/Isotype | Rabbit IgG |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human, Mouse |
Immunogen | This TNRC6A antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 855-885 amino acids from the Central region of human TNRC6A. |
Application | |
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WB | 1/1000-1/2000 |
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All lanes : Anti-TNRC6A Antibody (Center) at 1:1000-1:2000 dilution Lane 1: human skeletal muscle lysate Lane 2: Hela whole cell lysate Lane 3: MCF-7 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Predicted band size : 210 kDa Blocking/Dilution buffer: 5% NFDM/TBST. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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