Rabbit Polyclonal Antibody to TNXB

包装: 1G|100G|500G|1KG|100KG

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别名:XB; TNX; XBS; EDS3; HXBL; TENX; TN-X; TNXB1; TNXB2; TNXBS
应用:IHC
反应种属:Human
规格：50μl/100μl

Description
This gene encodes a member of the tenascin family of extracellular matrix glycoproteins. The tenascins have anti-adhesive effects, as opposed to fibronectin which is adhesive. This protein is thought to function in matrix maturation during wound healing, and its deficiency has been associated with the connective tissue disorder Ehlers-Danlos syndrome. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. It is one of four genes in this cluster which have been duplicated. The duplicated copy of this gene is incomplete and is a pseudogene which is transcribed but does not encode a protein. The structure of this gene is unusual in that it overlaps the CREBL1 and CYP21A2 genes at its 5′ and 3′ ends, respectively. Multiple transcript variants encoding different isoforms have been found for this gene.

Description

This gene encodes a member of the tenascin family of extracellular matrix glycoproteins. The tenascins have anti-adhesive effects, as opposed to fibronectin which is adhesive. This protein is thought to function in matrix maturation during wound healing, and its deficiency has been associated with the connective tissue disorder Ehlers-Danlos syndrome. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. It is one of four genes in this cluster which have been duplicated. The duplicated copy of this gene is incomplete and is a pseudogene which is transcribed but does not encode a protein. The structure of this gene is unusual in that it overlaps the CREBL1 and CYP21A2 genes at its 5′ and 3′ ends, respectively. Multiple transcript variants encoding different isoforms have been found for this gene.

Specification
Aliases	XB; TNX; XBS; EDS3; HXBL; TENX; TN-X; TNXB1; TNXB2; TNXBS
Swissprot	P22105
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Synthetic peptide of human TNXB
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Application
IHC	1/50-1/200
ELISA	1/3000-1/10000

	The image is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using P11378(TNXB Antibody) at dilution 1/30. (Original magnification: ×200)
	The image is immunohistochemistry of paraffin-embedded Human lung cancer tissue using P11378(TNXB Antibody) at dilution 1/30. (Original magnification: ×200)