Rabbit Polyclonal Antibody to TOP1MT

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别名:
应用:IHC
反应种属:Human
规格：50μl/100μl

Description
This gene encodes a mitochondrial DNA topoisomerase that plays a role in the modification of DNA topology. The encoded protein is a type IB topoisomerase and catalyzes the transient breaking and rejoining of DNA to relieve tension and DNA supercoiling generated in the mitochondrial genome during replication and transcription. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Description

This gene encodes a mitochondrial DNA topoisomerase that plays a role in the modification of DNA topology. The encoded protein is a type IB topoisomerase and catalyzes the transient breaking and rejoining of DNA to relieve tension and DNA supercoiling generated in the mitochondrial genome during replication and transcription. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Specification
Swissprot	Q969P6
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Synthetic peptide of human TOP1MT
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Application
IHC	1/5-1/20
ELISA	1/1000-1/2000

	The image is immunohistochemistry of paraffin-embedded Human gasrtic cancer tissue using P11138(TOP1MT Antibody) at dilution 1/10. (Original magnification: ×200)
	The image is immunohistochemistry of paraffin-embedded Human lung cancer tissue using P11138(TOP1MT Antibody) at dilution 1/10. (Original magnification: ×200)