中文 
别名:Neuronal tryptophan hydroxylase; NTPH; Tryptophan 5- monooxygenase 2;应用:WB
反应种属:Human
规格：50μl/100μl
| Description |
|---|
| This gene encodes a member of the pterin-dependent aromatic acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. The human genome contains two related tryptophan hydroxylases, one on chromosome 11p15-p14 and one on chromosome 12q21. This gene is expressed predominantly in the brain stem. Mutations in this gene may be associated with psychiatric diseases such as bipolar affective disorder and major depression.Bader M., Science 299:76-76(2003).Gibbs R.A., Nature 440:346-351(2006).Pandey A., Proc. Natl. Acad. Sci. U.S.A. 104:2199-2204(2007). |
| Specification | |
|---|---|
| Aliases | Neuronal tryptophan hydroxylase; NTPH; Tryptophan 5- monooxygenase 2; |
| Entrez GeneID | 121278; |
| Swissprot | Q8IWU9 |
| WB Predicted band size | 56kDa |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Synthesized non-phosphopeptide derived from human TPH2 around the phosphorylation site of serine 19 (G-FI-S(p)-L-D). |
| Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Application | |
|---|---|
| WB | 1/500-1/3000 |
 |
Western blot analysis of extracts from HuvEc cells (Lane 2), using TPH2 (Ab-19) antiobdy P41775. The lane on the left is treated with systhesized peptide. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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