Rabbit Polyclonal Antibody to TRIM24

包装: 1G|100G|500G|1KG|100KG

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别名:PTC6; TF1A; TIF1; RNF82; TIF1A; hTIF1; TIF1ALPHA
应用:WB,IHC
反应种属:Human, Mouse
规格：50μl/100μl

Description
The protein encoded by this gene mediates transcriptional control by interaction with the activation function 2 (AF2) region of several nuclear receptors, including the estrogen, retinoic acid, and vitamin D3 receptors. The protein localizes to nuclear bodies and is thought to associate with chromatin and heterochromatin-associated factors. The protein is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains – a RING, a B-box type 1 and a B-box type 2 – and a coiled-coil region.

Description

The protein encoded by this gene mediates transcriptional control by interaction with the activation function 2 (AF2) region of several nuclear receptors, including the estrogen, retinoic acid, and vitamin D3 receptors. The protein localizes to nuclear bodies and is thought to associate with chromatin and heterochromatin-associated factors. The protein is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains – a RING, a B-box type 1 and a B-box type 2 – and a coiled-coil region.

Specification
Aliases	PTC6; TF1A; TIF1; RNF82; TIF1A; hTIF1; TIF1ALPHA
Swissprot	O15164
WB Predicted band size	117/113 kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse
Immunogen	Synthetic peptide of human TRIM24
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Application
WB	1/500-1/2000
IHC	1/30-1/150
ELISA	1/2000-1/5000

	Gel: 6%SDS-PAGE, Lysate: 80 μg, Lane 1-3: 293T, 231 and lo2 cell, Primary antibody: P12286(TRIM24 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute
	The image is immunohistochemistry of paraffin-embedded Human breast cancer tissue using P12286(TRIM24 Antibody) at dilution 1/40. (Original magnification: ×200)