Rabbit Polyclonal Antibody to TRIM25

包装: 1G|100G|500G|1KG|100KG

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别名:EFP; Z147; RNF147; ZNF147
应用:IHC
反应种属:Human
规格：50μl/100μl

Description
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to the cytoplasm. The presence of potential DNA-binding and dimerization-transactivation domains suggests that this protein may act as a transcription factor, similar to several other members of the TRIM family. Expression of the gene is upregulated in response to estrogen, and it is thought to mediate estrogen actions in breast cancer as a primary response gene.

Description

The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to the cytoplasm. The presence of potential DNA-binding and dimerization-transactivation domains suggests that this protein may act as a transcription factor, similar to several other members of the TRIM family. Expression of the gene is upregulated in response to estrogen, and it is thought to mediate estrogen actions in breast cancer as a primary response gene.

Specification
Aliases	EFP; Z147; RNF147; ZNF147
Swissprot	Q14258
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Synthetic peptide of human TRIM25
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Application
IHC	1/10-1/50
ELISA	1/1000-1/2000

	The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P12293(TRIM25 Antibody) at dilution 1/25. (Original magnification: ×200)
	The image is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using P12293(TRIM25 Antibody) at dilution 1/25. (Original magnification: ×200)