Rabbit Polyclonal Antibody to TRIM69 (N-term)

包装: 1G|100G|500G|1KG|100KG

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别名:E3 ubiquitin-protein ligase TRIM69, 632-, RFP-like domain-containing protein trimless, RING finger protein 36, Tripartite motif-containing protein 69, TRIM69, RNF36
应用:WB,IHC
反应种属:Mouse
规格：50μl/100μl

Description
This gene encodes a member of the RING-B-box-coiled-coil (RBCC) family and encodes a protein with an N-terminal RING finger motif, a PRY domain and a C-terminal SPRY domain. The mouse ortholog of this gene is specifically expressed in germ cells at the round spermatid stages during spermatogenesis and, when overexpressed, induces apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been described. It may play a role in apoptosis (By similarity).

Description

This gene encodes a member of the RING-B-box-coiled-coil
(RBCC) family and encodes a protein with an N-terminal RING finger
motif, a PRY domain and a C-terminal SPRY domain. The mouse
ortholog of this gene is specifically expressed in germ cells at
the round spermatid stages during spermatogenesis and, when
overexpressed, induces apoptosis. Alternatively spliced transcript
variants encoding distinct isoforms have been described. It may play a role in apoptosis (By similarity).

Specification
Aliases	E3 ubiquitin-protein ligase TRIM69, 632-, RFP-like domain-containing protein trimless, RING finger protein 36, Tripartite motif-containing protein 69, TRIM69, RNF36
Entrez GeneID	140691
Swissprot	Q86WT6
WB Predicted band size	57.4kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Mouse
Immunogen	This TRIM69 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 101-129 amino acids from the N-terminal region of human TRIM69.
Formulation	Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Application
WB	1/1000
IHC	1/100-1/500

	TRIM69 Antibody (N-term) (Cat. #P31041) western blot analysis in mouse stomach tissue lysates (35ug/lane).This demonstrates the TRIM69 antibody detected the TRIM69 protein (arrow).
	TRIM69 Antibody (N-term) (Cat. #P31041)immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of TRIM69 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.