Rabbit Polyclonal Antibody to Trk

包装: 1G|100G|500G|1KG|100KG

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别名:gp140trk; GP145-TrkB; GP145-TrkC; MTC; NTRK1; NTRK2; NTRK3; p140-TrkA; TRKA; TRKB; TrkB tyrosine kinase; TRKC
应用:WB,IHC,ICC
反应种属:Human,Mouse,Rat
规格：50μl/100μl

Description
The family of Trk receptor tyrosine kinases consists of TrkA, TrkB, and TrkC. While the sequence of these family members is highly conserved, they are activated by different neurotrophins: TrkA by NGF, TrkB by BDNF or NT4, and TrkC by NT3. Neurotrophin signaling through these receptors regulates a number of physiological processes, such as cell survival, proliferation, neural development, and axon and dendrite growth and patterning.

Description

The family of Trk receptor tyrosine kinases consists of TrkA, TrkB, and TrkC. While the sequence of these family members is highly conserved, they are activated by different neurotrophins: TrkA by NGF, TrkB by BDNF or NT4, and TrkC by NT3. Neurotrophin signaling through these receptors regulates a number of physiological processes, such as cell survival, proliferation, neural development, and axon and dendrite growth and patterning.

Specification
Aliases	gp140trk; GP145-TrkB; GP145-TrkC; MTC; NTRK1; NTRK2; NTRK3; p140-TrkA; TRKA; TRKB; TrkB tyrosine kinase; TRKC
Entrez GeneID	4914/4916/4915
Swissprot	P04629/Q16288/Q16620
WB Predicted band size	Calculated MW: 87 kDa; Observed MW: 140 kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	A synthesized peptide derived from human TrkA+B+C
Formulation	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Application
WB	1/500-1/1000
IHC	1/50-1/100
ICC	1/50-1/200

	Western blot analysis of TrkA+B+C in Human fetal brain lysates using Trk antibody.
	Immunofluorescence analysis of Trk in Neuro2a using TrkA+B+C antibody.
	Immunohistochemistry analysis of paraffin-embedded mouse brain using TrkA+B+C antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.