Rabbit Polyclonal Antibody to TRPC6

包装: 1G|100G|500G|1KG|100KG

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别名:TRPC6;FSGS2;TRP6
应用:WB,IHC
反应种属:Human,Mouse,Rat
规格：50μl/100μl

Description
The protein encoded by this gene forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2).

Description

The protein encoded by this gene forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2).

Specification
Aliases	TRPC6;FSGS2;TRP6
Entrez GeneID	7225
Swissprot	Q9Y210
WB Predicted band size	106kDa
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	A synthetic peptide of human TRPC6 (NP_004612.2).
Formulation	PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Application
WB	1/500-1/2000
IHC	1/50-1/200

	Western blot analysis of extracts of Mouse pancreas, using TRPC6 antibody.
	Western blot analysis of extracts of Rat brain, using TRPC6 antibody.
	Immunohistochemistry of paraffin-embedded human esophageal cancer using TRPC6 Rabbit pAb.
	Immunohistochemistry of paraffin-embedded mouse kidney using TRPC6 Rabbit pAb.