中文 
别名:Hamartin, Tuberous sclerosis 1 protein, TSC1, KIAA0243, TSC应用:WB
反应种属:Human
规格：50μl/100μl
| Description |
|---|
| In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling. Seems not to be required for TSC2 GAP activity towards RHEB. Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling. |
| Specification | |
|---|---|
| Aliases | Hamartin, Tuberous sclerosis 1 protein, TSC1, KIAA0243, TSC |
| Entrez GeneID | 7248 |
| Swissprot | Q92574 |
| WB Predicted band size | 129.8kDa |
| Host/Isotype | Rabbit IgG |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This TSC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 395-424 amino acids from the Central region of human TSC1. |
| Formulation | Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Application | |
|---|---|
| WB | 1/1000 |
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TSC1 Antibody (Center T417) (Cat. #P32463) western blot analysis in SK-BR-3 cell line lysates (35ug/lane).This demonstrates the TSC1 antibody detected the TSC1 protein (arrow). |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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