中文 
别名:dual specificity protein kinase TTK; EC 2.7.12.1; Esk1; Mps1; MPS1L1应用:WB,IHC
反应种属:Human
规格：50μl/100μl
| Description |
|---|
| Phosphorylates proteins on serine, threonine, and tyrosine. Probably associated with cell proliferation. Essential for chromosome alignment by enhancing AURKB activity (via direct CDCA8 phosphorylation) at the centromere, and for the mitotic checkpoint.Mills G.B., J. Biol. Chem. 267:16000-16006(1992).Ota T., Nat. Genet. 36:40-45(2004).Mungall A.J., Nature 425:805-811(2003) |
| Specification | |
|---|---|
| Aliases | dual specificity protein kinase TTK; EC 2.7.12.1; Esk1; Mps1; MPS1L1 |
| Entrez GeneID | 7272; |
| Swissprot | P33981 |
| WB Predicted band size | 100kDa |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Synthesized non-phosphopeptide derived from human TTK around the phosphorylation site of threonine 676 (D-T-T(p)-S-V). |
| Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Application | |
|---|---|
| WB | 1/500-1/3000 |
| IHC | 1/50-1/100 |
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Western blot analysis of extracts from HUVEC cells, treated with etoposide (25uM, 24hours), using TTK (Ab-676) antibody P41729. |
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Western blot analysis of extracts from colo cells (Lane 2), using TTK (Ab-676) antiobdy P41729. The lane on the left is treated with synthesized peptide. |
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Immunohistochemistry analysis of paraffin-embedded human brain tissue using TTK (Ab-676) antibody P41729. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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