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瑞威尔生物科技 REVERE

Rabbit Polyclonal Antibody to UBE2K(N-term)

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别名:Ubiquitin-conjugating enzyme E2 K, Huntingtin-interacting protein 2, HIP-2, Ubiquitin carrier protein, Ubiquitin-conjugating enzyme E2-25 kDa, Ubiquitin-conjugating enzyme E2(25K), Ubiquitin-conjugating enzyme E2-25K, Ubiquitin-protein ligase, UBE2K, HIP2, LIG
应用:WB
反应种属:Human, Mouse
规格:50μl/100μl

Description
The protein encoded by this gene belongs to the
ubiquitin-conjugating enzyme family. This protein interacts with
RING finger proteins, and it can ubiquitinate huntingtin, the gene
product for Huntington’s disease. Known functions for this protein
include a role in aggregate formation of expanded polyglutamine
proteins and the suppression of apoptosis in polyglutamine
diseases, a role in the dislocation of newly synthesized MHC class
I heavy chains from the endoplasmic reticulum, and involvement in
foam cell formation. Multiple transcript variants encoding
different isoforms have been identified for this gene. [provided by
RefSeq].
Specification
Aliases Ubiquitin-conjugating enzyme E2 K, Huntingtin-interacting protein 2, HIP-2, Ubiquitin carrier protein, Ubiquitin-conjugating enzyme E2-25 kDa, Ubiquitin-conjugating enzyme E2(25K), Ubiquitin-conjugating enzyme E2-25K, Ubiquitin-protein ligase, UBE2K, HIP2, LIG
Entrez GeneID 3093
Swissprot P61086
WB Predicted band size 22.4kDa
Host/Isotype Rabbit IgG
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human, Mouse
Immunogen This UBE2K antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 2-30 amino acids from the N-terminal region of human UBE2K.
Formulation Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Application
WB 1/1000

Western blot analysis of lysates from Hela, 293 cell line, mouse brain tissue lysate, C2C12 cell line (from left to right), using UBE2K Antibody (N-term)(Cat. #P32625). P32625 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysates at 35ug per lane.

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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。