别名:Ubiquitin/ISG15-conjugating enzyme E2 L6, Retinoic acid-induced gene B protein, RIG-B, UbcH8, Ubiquitin carrier protein L6, Ubiquitin-protein ligase L6, UBE2L6, UBCH8应用:WB,IHC
反应种属:Human
规格:50μl/100μl
Description |
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The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). UBE2L6 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is demonstrated to function in the E6/E6-ap-induced ubiquitination of p53. |
Specification | |
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Aliases | Ubiquitin/ISG15-conjugating enzyme E2 L6, Retinoic acid-induced gene B protein, RIG-B, UbcH8, Ubiquitin carrier protein L6, Ubiquitin-protein ligase L6, UBE2L6, UBCH8 |
Entrez GeneID | 9246 |
Swissprot | O14933 |
WB Predicted band size | 17.8kDa |
Host/Isotype | Rabbit IgG |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | This UBE2L6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 123-153 amino acids from the C-terminal region of human UBE2L6. |
Formulation | Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
Application | |
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WB | 1/1000 |
IHC | 1/100-1/500 |
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Anti-UBE2L6 Antibody (K136) at 1:1000 dilution + MOLT-4 whole cell lysate
Lysates/proteins at 20 µg per lane. Secondary Predicted band size : 18 kDa Blocking/Dilution buffer: 5% NFDM/TBST. |
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Formalin-fixed and paraffin-embedded breast carcinoma tissue reacted with UBE2L6 Antibody (C-term)(Cat.#P33627), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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