Rabbit Polyclonal Antibody to UBE2N

包装: 1G|100G|500G|1KG|100KG

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别名:UBC13; UbcH13; HEL-S-71; UbcH-ben; UBCHBEN; UBC13
应用:WB,IHC
反应种属:Human, Mouse, Rat
规格：50μl/100μl

Description
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. Studies in mouse suggest that this protein plays a role in DNA postreplication repair.

Description

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. Studies in mouse suggest that this protein plays a role in DNA postreplication repair.

Specification
Aliases	UBC13; UbcH13; HEL-S-71; UbcH-ben; UBCHBEN; UBC13
Swissprot	P61088
WB Predicted band size	17 kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse, Rat
Immunogen	Synthetic peptide of human UBE2N
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Application
WB	1/500-1/2000
IHC	1/50-1/200
ELISA	1/5000-1/10000

	Gel: 12%SDS-PAGE, Lysate: 40 μg, Lane 1-5: Mouse brain tissue, Hela cell, LNCAP cell, HepG2 cell, Jurkat cell lysates, Primary antibody: P06020(UBE2N Antibody) at dilution 1/800, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 30 seconds
	The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P06020(UBE2N Antibody) at dilution 1/55. (Original magnification: ×200)
	The image is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using P06020(UBE2N Antibody) at dilution 1/55. (Original magnification: ×200)