Rabbit Polyclonal Antibody to VASP

包装: 1G|100G|500G|1KG|100KG

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别名:Vasodilator-stimulated phosphoprotein
应用:WB,IHC,ICC
反应种属:Human,Mouse,Rat,Monkey
规格：50μl/100μl

Description
VASP (vasodilator-stimulated phosphoprotein), is involved in the maintenance of cytoarchitecture by interacting with actin-like filaments. VASP shares a limited degree of homology with the amino terminus of WASP, which is frequently mutated in WAS patients. An established substrate of cAMP and cGMP dependent kinases, VASP is phosphorylated on a regulatory serine residue 157 and localizes to focal adhesions, microfilaments and highly active regions of the plasma membrane.

Description

VASP (vasodilator-stimulated phosphoprotein), is involved in the maintenance of cytoarchitecture by interacting with actin-like filaments. VASP shares a limited degree of homology with the amino terminus of WASP, which is frequently mutated in WAS patients. An established substrate of cAMP and cGMP dependent kinases, VASP is phosphorylated on a regulatory serine residue 157 and localizes to focal adhesions, microfilaments and highly active regions of the plasma membrane.

Specification
Aliases	Vasodilator-stimulated phosphoprotein
Entrez GeneID	7408
Swissprot	P50552
WB Predicted band size	Calculated MW: 40 kDa; Observed MW: 46,50 kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat,Monkey
Immunogen	The antiserum was produced against synthesized peptide derived from human VASP. AA range:124-173
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Application
WB	1/500-1/1000
IHC	1/50-1/100
ICC	1/50-1/200
ELISA	1/10000

	Western blot analysis of VASP in various lysates using VASP antibody.
	Western blot analysis of VASP in NIH/3T3 lysates treated with forskolin using VASP antibody. The lane on the right is blocked with the synthesized peptide.