别名:Proto-oncogene vav; VAV1; VAV;应用:WB
反应种属:Human
规格:50μl/100μl
Description |
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Couples tyrosine kinase signals with the activation of the Rho/Rac GTPases, thus leading to cell differentiation and/or proliferation.Ana V. Miletic, J. Biol. Chem., Dec 2006; 281: 38257 – 38265.Christopher C. Stebbins, Mol. Cell. Biol., Sep 2003; 23: 6291 – 6299.Vered Schapira, Cancer Res., Jun 2006; 66: 6183 – 6191.Maya Groysman, J. Biol. Chem., Dec 2002; 277: 50121 – 50130. |
Specification | |
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Aliases | Proto-oncogene vav; VAV1; VAV; |
Entrez GeneID | 7409; |
Swissprot | P15498 |
WB Predicted band size | 95kDa |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Synthesized non-phosphopeptide derived from human VAV1 around the phosphorylation site of tyrosine 174 (E-I-Y-E-D). |
Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Application | |
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WB | 1/500-1/3000 |
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Western blot analysis of extracts from Jurkat cells, using VAV1 (Ab-174) antibody P41696. |
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Western blot analysis of extracts from JK cells (Lane 2), using VAV1 (Ab-174) antiobdy P41696. The lane on the left is treated with synthesized peptide. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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