中文 
别名:VAV3; FLJ40431; Guanine nucleotide exchange factor VAV3;应用:WB
反应种属:Human
规格：50μl/100μl
| Description |
|---|
| This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.Trenkle T., Nucleic Acids Res. 26:3883-3891(1998)Movilla N., Mol. Cell. Biol. 19:7870-7885(1999) |
| Specification | |
|---|---|
| Aliases | VAV3; FLJ40431; Guanine nucleotide exchange factor VAV3; |
| Entrez GeneID | 10451; |
| Swissprot | Q9UKW4 |
| WB Predicted band size | 100kDa |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Peptide sequence around phosphorylation site of tyrosine 173 (E-V-Y(p)-E-D) derived from Human VAV3. |
| Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Application | |
|---|---|
| WB | 1/500-1/1000 |
 |
Western blot analysis of extracts from JK cells using VAV3 (Phospho-Tyr173) Antibody P40529.The lane on the right is treated with the antigen-specific peptide. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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