Rabbit Polyclonal Antibody to VCX1 (N-term)

包装: 1G|100G|500G|1KG|100KG

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别名:Variable charge X-linked protein 1, Variable charge protein on X with ten repeats, VCX-10r, Variably charged protein X-B1, VCX-B1, VCX, VCX1, VCX10R, VCXB1
应用:WB,IHC
反应种属:Human
规格：50μl/100μl

Description
This gene belongs to the VCX/Y gene family, which has multiple members on both X and Y chromosomes, and all are expressed exclusively in male germ cells. The X-linked members are clustered on chromosome Xp22 and Y-linked members are two identical copies of the gene within a palindromic region on Yq11. The family members share a high degree of sequence identity, with the exception that a 30-bp unit is tandemly repeated in X-linked members but occurs only once in Y-linked members. The VCX gene cluster is polymorphic in terms of copy number; different individuals may have a different number of VCX genes. VCX/Y genes encode small and highly charged proteins of unknown function. The presence of a putative bipartite nuclear localization signal suggests that VCX/Y members are nuclear proteins. This gene contains 10 repeats of the 30-bp unit.

Description

This gene belongs to the VCX/Y gene family, which has
multiple members on both X and Y chromosomes, and all are expressed
exclusively in male germ cells. The X-linked members are clustered
on chromosome Xp22 and Y-linked members are two identical copies of
the gene within a palindromic region on Yq11. The family members
share a high degree of sequence identity, with the exception that a
30-bp unit is tandemly repeated in X-linked members but occurs only
once in Y-linked members. The VCX gene cluster is polymorphic in
terms of copy number; different individuals may have a different
number of VCX genes. VCX/Y genes encode small and highly charged
proteins of unknown function. The presence of a putative bipartite
nuclear localization signal suggests that VCX/Y members are nuclear
proteins. This gene contains 10 repeats of the 30-bp unit.

Specification
Aliases	Variable charge X-linked protein 1, Variable charge protein on X with ten repeats, VCX-10r, Variably charged protein X-B1, VCX-B1, VCX, VCX1, VCX10R, VCXB1
Entrez GeneID	26609
Swissprot	Q9H320
WB Predicted band size	22.3kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	This VCX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human VCX1.
Formulation	Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Application
WB	1/1000
IHC	1/100-1/500

	VCX1/VCX2/VCX3 Antibody (N-term) (Cat. #P30859) western blot analysis in A2058,MCF-7,MDA-MB453 cell line lysates (35ug/lane).This demonstrates the VCX1/VCX2/VCX3 antibody detected the VCX1/VCX2/VCX3 protein (arrow).
	VCX1 Antibody (N-term) (Cat. #P30859) immunohistochemistry analysis in formalin fixed and paraffin embedded human testis carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the VCX1 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.