Rabbit Polyclonal Antibody to VDAC1

包装: 1G|100G|500G|1KG|100KG

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别名:VDAC1; PORIN; PORIN-31-HL
应用:WB,IHC
反应种属:Human,Mouse,Rat
规格：50μl/100μl

Description
Voltage-dependent anion channel (VDAC), ubiquitously expressed and located in the outer mitochondrial membrane, is generally thought to be the primary means by which metabolites diffuse in and out of the mitochondria. In addition, this channel plays a role in apoptotic signaling. The change in mitochondrial permeability characteristic of apoptosis is mediated by Bcl-2 family proteins, which bind to VDAC, altering the channel kinetics.

Description

Voltage-dependent anion channel (VDAC), ubiquitously expressed and located in the outer mitochondrial membrane, is generally thought to be the primary means by which metabolites diffuse in and out of the mitochondria. In addition, this channel plays a role in apoptotic signaling. The change in mitochondrial permeability characteristic of apoptosis is mediated by Bcl-2 family proteins, which bind to VDAC, altering the channel kinetics.

Specification
Aliases	VDAC1; PORIN; PORIN-31-HL
Entrez GeneID	7416
Swissprot	P21796
WB Predicted band size	Calculated MW: 31 kDa; Observed MW: 31 kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	A synthesized peptide derived from human VDAC1
Formulation	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Application
WB	1/500-1/1000
IHC	1/50-1/100

	Western blot analysis of Calreticulin in (1) HepG2 lysates; (2) Jurkat lysates using VDAC1 antibody.
	Western blot analysis of VDAC1 in C2C12, THP-1, 3T3, Jurakt and Hela lysates using VDAC1 antibody
	Immunohistochemistry analysis of paraffin-embedded Human liver using VDAC1 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.