中文 
别名:Vascular endothelial cadherin; VE-cadherin; 7B4 antigen; CDH5; CD144 antigen应用:WB
反应种属:Human,Mouse,Rat
规格：50μl/100μl
| Description |
|---|
| Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. This cadherin may play a important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. It associates with alpha-catenin forming a link to the cytoskeleton. Acts in concert with KRIT1 to establish and maintain correct endothelial cell polarity and vascular lumen. Wessel F, et al. (2014) Nat Immunol 15, 223-30 Sawada J, et al. (2012) Cancer Cell 22, 235-49 Turowski P, et al. (2008) J Cell Sci 121, 29-37 |
| Specification | |
|---|---|
| Aliases | Vascular endothelial cadherin; VE-cadherin; 7B4 antigen; CDH5; CD144 antigen |
| Entrez GeneID | 1003; |
| Swissprot | P33151 |
| WB Predicted band size | 130kDa |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | Peptide sequence around phosphorylation site of Tyrosine731 (H-I-Y(p)-G-Y) derived from Human VE-Cadherin. |
| Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Application | |
|---|---|
| WB | 1/500-1/1000 |
 |
Western blot analysis of extracts from HepG2 cells treated with Na3VO4 using Phospho-VE-Cadherin (Tyr731) antibody P40587.The lane on the right is treated with the antigen-specific peptide. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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