Rabbit Polyclonal Antibody to VEGF3 (N-term)

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别名:Vascular endothelial growth factor C, VEGF-C, Flt4 ligand, Flt4-L, Vascular endothelial growth factor-related protein, VRP, VEGFC
应用:WB,IHC,FCM
反应种属:Human
规格：50μl/100μl

Description
The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family, is active in angiogenesis and endothelial cell growth, and can also affect the permeability of blood vessels. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-3 receptors. Only the fully processed form can bind and activate VEGFR-2 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor D. [provided by RefSeq].

Description

The protein encoded by this gene is a member of the
platelet-derived growth factor/vascular endothelial growth factor
(PDGF/VEGF) family, is active in angiogenesis and endothelial cell
growth, and can also affect the permeability of blood vessels.
This secreted protein undergoes a complex proteolytic maturation,
generating multiple processed forms which bind and activate VEGFR-3
receptors. Only the fully processed form can bind and activate
VEGFR-2 receptors. This protein is structurally and functionally
similar to vascular endothelial growth factor D. [provided by
RefSeq].

Specification
Aliases	Vascular endothelial growth factor C, VEGF-C, Flt4 ligand, Flt4-L, Vascular endothelial growth factor-related protein, VRP, VEGFC
Entrez GeneID	7424
Swissprot	P49767
WB Predicted band size	46.9kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	This VEGF3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 20-49 amino acids from the N-terminal region of human VEGF3.
Formulation	Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Application
WB	1/1000
IHC	1/100-1/500
FCM	1/10-1/50

	Anti-VEGF3 Antibody (N-term) at 1:1000 dilution + K562 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 47 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
	VEGF3 Antibody (N-term) (Cat. #P33525) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the VEGF3 antibody detected the VEGF3 protein (arrow).
	VEGF3 Antibody (N-term) (Cat. #P33525) flow cytometric analysis of MCF-7 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
	VEGF3 Antibody (N-term) (Cat. #P33525)immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of VEGF3 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.