Rabbit Polyclonal Antibody to VSNL1

包装: 1G|100G|500G|1KG|100KG

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别名:Visinin-like protein 1, VILIP, VLP-1, Hippocalcin-like protein 3, HLP3, VSNL1, VISL1
应用:WB,IHC,FCM
反应种属:Human, Mouse
规格：50μl/100μl

Description
This gene is a member of the visinin/recoverin subfamily of neuronal calcium sensor proteins. The encoded protein is strongly expressed in granule cells of the cerebellum where it associates with membranes in a calcium-dependent manner and modulates intracellular signaling pathways of the central nervous system by directly or indirectly regulating the activity of adenylyl cyclase. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined.

Description

This gene is a member of the visinin/recoverin subfamily
of neuronal calcium sensor proteins. The encoded protein is
strongly expressed in granule cells of the cerebellum where it
associates with membranes in a calcium-dependent manner and
modulates intracellular signaling pathways of the central nervous
system by directly or indirectly regulating the activity of
adenylyl cyclase. Alternatively spliced transcript variants have
been observed, but their full-length nature has not been
determined.

Specification
Aliases	Visinin-like protein 1, VILIP, VLP-1, Hippocalcin-like protein 3, HLP3, VSNL1, VISL1
Entrez GeneID	7447
Swissprot	P62760
WB Predicted band size	22.1kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse
Immunogen	This VSNL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 47-75 amino acids from the Central region of human VSNL1.
Formulation	Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Application
WB	1/1000
IHC	1/100-1/500
FCM	1/10-1/50

	Western blot analysis of VSNL1 (arrow) using rabbit polyclonal VSNL1 Antibody (Center) (Cat. #P31052). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the VSNL1 gene.
	VSNL1 Antibody (Center) (Cat. #P31052) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the VSNL1 antibody detected the VSNL1 protein (arrow).
	VSNL1 Antibody (Center) (Cat. #P31052) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
	VSNL1 Antibody (Center) (Cat. #P31052)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of VSNL1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.