Rabbit Polyclonal Antibody to WFDC1 (C-term H163)

包装: 1G|100G|500G|1KG|100KG

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别名:WAP four-disulfide core domain protein 1, Prostate stromal protein ps20, ps20 growth inhibitor, WFDC1, PS20
应用:WB
反应种属:Human
规格：50μl/100μl

Description
This gene encodes a member of the WAP-type four disulfide core domain family. The WAP-type four-disulfide core domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. The encoded protein shares 81% amino acid identity with the rat ps20 protein, which was originally identified as a secreted growth inhibitor. This gene is mapped to chromosome 16q24, an area of frequent loss of heterozygosity in cancers, including prostate, breast and hepatocellular cancers and Wilms’ tumor. Owing to its location and a possible growth inhibitory property of its gene product, this gene is suggested to be a tumor suppressor gene.

Description

This gene encodes a member of the WAP-type four disulfide
core domain family. The WAP-type four-disulfide core domain, or WAP
signature motif, contains eight cysteines forming four disulfide
bonds at the core of the protein, and functions as a protease
inhibitor in many family members. The encoded protein shares 81%
amino acid identity with the rat ps20 protein, which was originally
identified as a secreted growth inhibitor. This gene is mapped to
chromosome 16q24, an area of frequent loss of heterozygosity in
cancers, including prostate, breast and hepatocellular cancers and
Wilms’ tumor. Owing to its location and a possible growth
inhibitory property of its gene product, this gene is suggested to
be a tumor suppressor gene.

Specification
Aliases	WAP four-disulfide core domain protein 1, Prostate stromal protein ps20, ps20 growth inhibitor, WFDC1, PS20
Entrez GeneID	58189
Swissprot	Q9HC57
WB Predicted band size	24.0kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	This WFDC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 148-177 amino acids from the C-terminal region of human WFDC1.
Formulation	Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.