中文 
别名:DKCB3; TCAB1; WDR79应用:WB
反应种属:Human, Rat
规格：50μl/100μl
| Description |
|---|
| This gene encodes an essential component of the telomerase holoenzyme complex, a ribonucleoprotein complex required for telomere synthesis. This protein is enriched in Cajal bodies, nuclear sites of RNP processing that are important for telomerase function. It interacts with dyskerin, TERT and TERC, other components of active telomerase, and with small Cajal body RNAs (scaRNAs), which are involved in modifying splicing RNAs. This mRNA also functions as a p53 antisense transcript, that regulates endogenous p53 mRNA levels and further induction of p53 protein by targeting the 5′ untranslated region of p53 mRNA. Alternatively spliced transcript variants which differ only in the 5′ UTR have been found for this gene. |
| Specification | |
|---|---|
| Aliases | DKCB3; TCAB1; WDR79 |
| Swissprot | Q9BUR4 |
| WB Predicted band size | 59 kDa |
| Host/Isotype | Rabbit IgG |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Rat |
| Immunogen | Fusion protein of human WRAP53 |
| Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Application | |
|---|---|
| WB | 1/500-1/2000 |
| ELISA | 1/5000-1/10000 |
 |
Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-3: Raji, 231 and Jurkat cell lysates, Primary antibody: P13886(WRAP53 Antibody) at dilution 1/550, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 3 minutes |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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