Rabbit Polyclonal Antibody to XRCC6

包装: 1G|100G|500G|1KG|100KG

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别名:ML8, KU70, TLAA, CTC75, CTCBF, G22P1
应用:IHC
反应种属:Human, Mouse
规格：50μl/100μl

Description
The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus.

Description

The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus.

Specification
Aliases	ML8, KU70, TLAA, CTC75, CTCBF, G22P1
Swissprot	P12956
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse
Immunogen	Fusion protein of human XRCC6
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Application
IHC	1/10-1/50
ELISA	1/1000-1/5000

	The image is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using P07411(XRCC6 Antibody) at dilution 1/10. (Original magnification: ×200)
	The image is immunohistochemistry of paraffin-embedded Human colon cancer tissue using P07411(XRCC6 Antibody) at dilution 1/10. (Original magnification: ×200)