中文 
别名:CBF-A; NSEP1; EFI-A; MSY-1; YBX1应用:WB
反应种属:Human,Mouse,Rat
规格：50μl/100μl
| Description |
|---|
| YB-1 is a nuclear protein that binds to splice sites in pre-mRNA and regulates splice site selection. Binds and stabilizes cytoplasmic mRNA. Contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors CCAAT-containing Y-box of HLA class II genes. Component of cytoplasmic messenger ribonucleoprotein particles (mRNPs). Interacts with AKT1, SFRS9, THOC4, MSH2, XRCC5, WRN and NCL. Can bind to DNA as a homomeric form, (EFI-A)n or as a heteromeric form in association with EFI-B. Homodimer in the presence of ATP.Sakura H., Gene 73:499-507(1988)Didier D.K. Proc. Natl. Acad. Sci. U.S.A. 85:7322-7326(1988)Kolluri R., Nucleic Acids Res. 19:4771-4771(1991) |
| Specification | |
|---|---|
| Aliases | CBF-A; NSEP1; EFI-A; MSY-1; YBX1 |
| Entrez GeneID | 4904; |
| Swissprot | P67809 |
| WB Predicted band size | 36kDa |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | Peptide sequence around phosphorylation site of Serine 102(L-R-S(p)-V-G) derived from Human YB1. |
| Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Application | |
|---|---|
| WB | 1/500-1/1000 |
 |
Western blot analysis of extracts from HepG2 cells treated with PMA using YB1 (Phospho-Ser102) Antibody P40518.The lane on the right is treated with the antigen-specific peptide. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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