别名:Zinc finger CCCH domain-containing protein 8; ZC3H8; ZC3HDC8;应用:WB,IHC
反应种属:Human
规格:50μl/100μl
Description |
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Acts as a transcriptional repressor of the GATA3 promoter. Sequence-specific DNA-binding factor that binds to the 5′-AGGTCTC-3′ sequence within the negative cis-acting element intronic regulatory region (IRR) of the GATA3 gene By similarity. Induces thymocyte apoptosis when overexpressed, which may indicate a role in regulation of thymocyte homeostasis.Zhuang D.Z., Submitted (JAN-2001) to the EMBL/GenBank/DDBJ databases.The MGC Project Team, Genome Res. 14:2121-2127(2004).Hwang E.S., Immunology 106:464-469(2002). |
Specification | |
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Aliases | Zinc finger CCCH domain-containing protein 8; ZC3H8; ZC3HDC8; |
Entrez GeneID | 84524; |
Swissprot | Q8N5P1 |
WB Predicted band size | 40kDa |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Synthesized peptide derived from internal of human ZC3H8. |
Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Application | |
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WB | 1/500-1/3000 |
IHC | 1/50-1/100 |
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Western blot analysis of extracts from HepG2 cells, using ZC3H8 antibody P42671. |
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Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using ZC3H8 antibody P42671. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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