别名:EC 2.3.1.-; ZDH7; ZDHC7; zinc finger 370; ZNF370应用:WB
反应种属:Human,Mouse,Rat
规格:50μl/100μl
Description |
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Palmitoyltransferase with broad specificity. Palmitoylates SNAP25 and DLG4/PSD95. May palmitoylate GABA receptors on their gamma subunit (GABRG1, GABRG2 and GABRG3) and thereby regulate their synaptic clustering and/or cell surface stability By similarity. Palmitoylates sex steroid hormone receptors, including ESR1, PGR and AR, thereby regulating their targeting to the plasma membrane. This affects rapid intracellular signaling by sex hormones via ERK and AKT kinases and the generation of cAMP, but does not affect that mediated by their nuclear receptors.Ota T., Nat. Genet. 36:40-45(2004).The MGC Project Team; Genome Res. 14:2121-2127(2004).Sjoeblom T., Science 314:268-274(2006) |
Specification | |
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Aliases | EC 2.3.1.-; ZDH7; ZDHC7; zinc finger 370; ZNF370 |
Entrez GeneID | 55625; |
Swissprot | Q9NXF8 |
WB Predicted band size | 35kDa |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human,Mouse,Rat |
Immunogen | Synthesized peptide derived from C-terminal of human ZDHHC7. |
Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Application | |
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WB | 1/500-1/3000 |
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Western blot analysis of extracts from HUVEC cells, using ZDHHC7 antibody P42513. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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