Rabbit Polyclonal Antibody to ZMYND10

包装: 1G|100G|500G|1KG|100KG

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别名:Zinc finger MYND domain-containing protein 10, Protein BLu, ZMYND10, BLU
应用:WB,IHC,FCM
反应种属:Human
规格：50μl/100μl

Description
BLU is a candidate tumor suppressor gene, that spans 4.5 kb on 3p21.3. It encodes a 50 kd protein, which is commonly found in transcription repressors. It is suspected that BLU has a function in cell cycle progression. BLU is a stress-responsive gene regulated by E2F.12 It is commonly found to be downregulated in non-small cell lung cancer, esophagus squamous cell carcinoma and nasopharyngeal carcinoma (NPC).

Description

BLU is a candidate tumor suppressor gene, that spans 4.5 kb on 3p21.3. It encodes a 50 kd protein, which is commonly found in transcription repressors. It is suspected that BLU has a function in cell cycle progression. BLU is a stress-responsive gene regulated by E2F.12 It is commonly found to be downregulated in non-small cell lung cancer, esophagus squamous cell carcinoma and nasopharyngeal carcinoma (NPC).

Specification
Aliases	Zinc finger MYND domain-containing protein 10, Protein BLu, ZMYND10, BLU
Entrez GeneID	51364
Swissprot	O75800
WB Predicted band size	50.3kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	This ZMYND10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 321-348 amino acids from the Central region of human ZMYND10.
Formulation	Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Application
WB	1/1000
IHC	1/100-1/500
FCM	1/10-1/50

	ZMYND10 Antibody (Center) (Cat. #P31039) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the ZMYND10 antibody detected the ZMYND10 protein (arrow).
	ZMYND10 Antibody (Center) (Cat. #P31039) flow cytometric analysis of CEM cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
	ZMYND10 Antibody (Center) (Cat. #P31039)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of ZMYND10 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.