别名:SBF; STAF; pHZ-1应用:IHC
反应种属:Human, Mouse, Rat
规格:50μl/100μl
Description |
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ZNF143 (zinc finger protein 143), also known as SBF, STAF or pHZ-1, is a 626 amino acid protein that contains seven C2H2-type zinc fingers and belongs to the GLI (glioma-associated oncogene) C2H2-type zinc-finger family. Localized to the nucleus and expressed ubiquitously with highest expression in ovaries, ZNF143 functions as a transcriptional activator that, via its C2H2-type zinc domains, binds to the SPH motif found in the promotors of small nuclear RNAs (snRNA). Through its ability to bind the promotors of various snRNA genes, ZNF143 controls the subsequent expression of the corresponding protein products. ZNF143 expression is induced upon DNA damage, suggesting an important role for ZNF143 in DNA repair events. |
Specification | |
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Aliases | SBF; STAF; pHZ-1 |
Swissprot | P52747 |
Host/Isotype | Rabbit IgG |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human, Mouse, Rat |
Immunogen | Synthetic peptide of human ZNF143 |
Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Application | |
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IHC | 1/10-1/50 |
ELISA | 1/5000-1/10000 |
The image is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using P05961(ZNF143 Antibody) at dilution 1/20. (Original magnification: ×200) |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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