Rabbit Polyclonal Antibody to ZNHIT1

包装: 1G|100G|500G|1KG|100KG

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别名:CG1I; ZNFN4A1
应用:WB,IHC
反应种属:Human, Mouse
规格：50μl/100μl

Description
ZNHIT1 (zinc finger, HIT-type containing 1), also known as CG1I (cyclin-G1-binding protein 1), p18 hamlet or ZNFN4A1 (zinc finger protein subfamily 4A member 1), is a 154 amino acid protein that plays a role in the induction of p53-mediated apoptosis. A member of the ZNHIT1 family, ZNHIT1 contains one HIT-type zinc finger and interacts with p38. ZNHIT1 undergoes post-translational phosphorylation and is encoded by a gene that maps to human chromosome 7, which houses over 1,000 genes and comprises nearly 5% of the human genome. Chromosome 7 has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. The deletion of a portion of the q arm of chromosome 7 is associated with Williams-Beuren syndrome, a condition characterized by mild mental retardation, an unusual comfort and friendliness with strangers and an elfin appearance.

Description

ZNHIT1 (zinc finger, HIT-type containing 1), also known as CG1I (cyclin-G1-binding protein 1), p18 hamlet or ZNFN4A1 (zinc finger protein subfamily 4A member 1), is a 154 amino acid protein that plays a role in the induction of p53-mediated apoptosis. A member of the ZNHIT1 family, ZNHIT1 contains one HIT-type zinc finger and interacts with p38. ZNHIT1 undergoes post-translational phosphorylation and is encoded by a gene that maps to human chromosome 7, which houses over 1,000 genes and comprises nearly 5% of the human genome. Chromosome 7 has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. The deletion of a portion of the q arm of chromosome 7 is associated with Williams-Beuren syndrome, a condition characterized by mild mental retardation, an unusual comfort and friendliness with strangers and an elfin appearance.

Specification
Aliases	CG1I; ZNFN4A1
Swissprot	O43257
WB Predicted band size	18 kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse
Immunogen	Full length fusion protein
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Application
WB	1/500-1/2000
IHC	1/30-1/150
ELISA	1/5000-1/10000

	Gel: 12%SDS-PAGE, Lysate: 40 μg, Lane: 293T cell lysate , Primary antibody: P09026(ZNHIT1 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds
	The image is immunohistochemistry of paraffin-embedded Human tonsil tissue using P09026(ZNHIT1 Antibody) at dilution 1/40. (Original magnification: ×200)
	The image is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using P09026(ZNHIT1 Antibody) at dilution 1/40. (Original magnification: ×200)